When increased dose equals increased severity of tissue reactions, this is called:

When increased dose equals increased severity of tissue reactions, this is called:

• A. probabilistic
• B. stochastic
• C. deterministic
• D. mutagenic

Answer: (C)

Deterministic effects produce a dose–response relationship where increasing dose leads to greater severity of tissue reactions, and there is a threshold below which little or no effect occurs. As the dose rises past that threshold, the damage becomes more severe. This is different from stochastic effects, where the chance of occurrence increases with dose but the severity of the effect is not dose-dependent. Mutagenic effects relate to genetic mutations rather than immediate tissue damage. So the scenario described—higher dose causing more severe tissue reactions—fits deterministic effects (for example, increasing skin erythema or cataract severity with higher doses).

Deterministic effects produce a dose–response relationship where increasing dose leads to greater severity of tissue reactions, and there is a threshold below which little or no effect occurs. As the dose rises past that threshold, the damage becomes more severe. This is different from stochastic effects, where the chance of occurrence increases with dose but the severity of the effect is not dose-dependent. Mutagenic effects relate to genetic mutations rather than immediate tissue damage. So the scenario described—higher dose causing more severe tissue reactions—fits deterministic effects (for example, increasing skin erythema or cataract severity with higher doses).